Upstream Bio Inc.
Last updated September 27, 2026
Organization details
- Legal name
- Upstream Bio Inc.
- Ownership
- Public
- Status
- Active
- Headquarters country
- United States
- Ticker symbol
- UPB
- Primary stock exchange
- Nasdaq
Identifiers
- SEC CIK
- 0002022626
Board of directors
-
Daniella Beckman · DirectorSince 2024
-
Erez Chimovits · DirectorSince 2024
-
Everett Rand Sutherland · Director · Chief Executive OfficerSince 2024
-
Harold Edward Fleming · DirectorSince 2024
-
Liam Ratcliffe · DirectorSince 2024
-
Marcella K. Ruddy · DirectorSince 2024
-
Ronald C. Renaud Jr. · DirectorSince 2024
Chief executives
Everett Rand Sutherland
· Chief Executive Officer
Since October 2024
Board connections
7 of this board's directors also sit on 10 other boards.
- via Harold Edward Fleming and Marcella K. Ruddy
- via Erez Chimovits
- via Erez Chimovits
- via Harold Edward Fleming
- via Liam Ratcliffe
- via Liam Ratcliffe
- via Ronald C. Renaud Jr.
- via Everett Rand Sutherland
- via Liam Ratcliffe
- via Daniella Beckman
Insider trades
All notable trades →From SEC Forms 4 and 5. Open-market purchases and sales are highlighted; grants, option exercises and shares withheld for tax are routine.
- Bought, last 12 months
- $0
- 0 purchases by 0 insiders
- Sold, last 12 months
- $104,796
- 15 sales by 5 insiders
| Date | Insider | Transaction | Shares | Price | Value |
|---|---|---|---|---|---|
| Sep 16, 2026 | Ambrose Allison Officer (General Counsel) | Open-market sale | −485 | $5.49 | $2,663 |
| Sep 16, 2026 | Deykin Aaron Officer (Chief Medical Officer) | Open-market sale | −895 | $5.49 | $4,914 |
| Sep 16, 2026 | GRAY MICHAEL Officer (CFO and COO) | Open-market sale | −853 | $5.49 | $4,683 |
| Sep 16, 2026 | Houghton Adam Officer (Chief Business Officer) | Open-market sale | −700 | $5.49 | $3,843 |
| Sep 16, 2026 | Everett Rand Sutherland Director, Officer (Chief Executive Officer) | Open-market sale | −2,095 | $5.49 | $11,502 |
| Jun 16, 2026 | GRAY MICHAEL Officer (CFO and COO) | Open-market sale | −853 | $6.10 | $5,203 |
| Jun 16, 2026 | Everett Rand Sutherland Director, Officer (Chief Executive Officer) | Open-market sale | −2,095 | $6.10 | $12,780 |
| Jun 16, 2026 | Houghton Adam Officer (Chief Business Officer) | Open-market sale | −700 | $6.10 | $4,270 |
| Jun 16, 2026 | Deykin Aaron Officer (Chief Medical Officer) | Open-market sale | −895 | $6.10 | $5,460 |
| Jun 16, 2026 | Ambrose Allison Officer (General Counsel) | Open-market sale | −477 | $6.10 | $2,910 |
| Mar 16, 2026 | GRAY MICHAEL Officer (CFO and COO) | Open-market sale | −852 | $9.29 | $7,915 |
| Mar 16, 2026 | Deykin Aaron Officer (Chief Medical Officer) | Open-market sale | −894 | $9.29 | $8,305 |
| Mar 16, 2026 | Everett Rand Sutherland Director, Officer (Chief Executive Officer) | Open-market sale | −2,093 | $9.29 | $19,444 |
| Mar 16, 2026 | Ambrose Allison Officer (General Counsel) | Open-market sale | −475 | $9.29 | $4,413 |
| Mar 16, 2026 | Houghton Adam Officer (Chief Business Officer) | Open-market sale | −699 | $9.29 | $6,494 |
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