Xilio Therapeutics Inc.

Last updated September 27, 2026

Organization details

Legal name
Xilio Therapeutics Inc.
Ownership
Public
Status
Active
SIC code
2834 — Pharmaceutical Preparations
Jurisdiction of incorporation
Delaware
Headquarters city
Waltham
Headquarters state / province
Massachusetts
Headquarters country
United States
Fiscal year end
December
Ticker symbol
XLO
Primary stock exchange
Nasdaq

Identifiers

SEC CIK
0001840233
EIN
85-1623397

Board of directors

Chief executives

Rene Russo · PRESIDENT AND CEO
Dates unknown

Director election results

Annual meeting of June 10, 2026. Support is votes for as a share of votes for and against (or withheld). Below 80% is a clear protest.

Board connections

10 of this board's directors also sit on 16 other boards.

Network of Xilio Therapeutics Inc.'s board connections ALX Oncology Holdings Inc. ALX Oncology Holdings... Anika Therapeutics Inc. Anika Therapeutics Inc... CG Oncology Inc. CG Oncology Inc. Climb Bio Inc. Climb Bio Inc. Dare Bioscience Inc. Dare Bioscience Inc. Exelixis Inc. Exelixis Inc. Fate Therapeutics Inc. Fate Therapeutics Inc. Incyte Corp. Incyte Corp. Invivyd Inc. Invivyd Inc. Kyntra Bio Inc. Kyntra Bio Inc. Latigo Biotherapeutics Inc. Latigo Biotherapeutics... Legend Biotech Corporation Legend Biotech Corpora... MannKind Corporation MannKind Corporation Obsidian Therapeutics Inc. Obsidian Therapeutics... ProQR Therapeutics N.V. ProQR Therapeutics N.V... Sionna Therapeutics Inc. Sionna Therapeutics In... Aoife Brennan Aoife Brennan Cheryl R. Blanchard Cheryl R. Blanchard Christina Rossi Christina Rossi Daniel J. Curran Daniel J. Curran James Samuel Shannon James Samuel Shannon Paul J. Clancy Paul J. Clancy Robert W. Ross Robert W. Ross Sara Bonstein Sara Bonstein Tomas J. Heyman Tomas J. Heyman Yuan Xu Yuan Xu Xilio Therapeutics Inc.
Shared director Other board Same sector

Insider trades

All notable trades →

From SEC Forms 4 and 5. Open-market purchases and sales are highlighted; grants, option exercises and shares withheld for tax are routine.

Bought, last 12 months
$43,950
1 purchase by 1 insider
Sold, last 12 months
$5,668
2 sales by 2 insiders
Date Insider Transaction Shares Price Value
Mar 26, 2026 James Samuel Shannon Director Open-market purchase +5,000 $8.79 $43,950
Jan 2, 2026 Brennan Kevin M. Officer (SVP, FINANCE AND ACCOUNTING) Open-market sale −1,826 $0.64 $1,169
Jan 2, 2026 Frankenfield Christopher James Officer (Chief Financial Officer) Open-market sale −7,030 $0.64 $4,499
Jan 1, 2026 Luptakova Katarina Officer (CHIEF MEDICAL OFFICER) Option exercise +16,625 — —
Jan 1, 2026 Brennan Kevin M. Officer (SVP, FINANCE AND ACCOUNTING) Option exercise +5,000 — —
Jan 1, 2026 Frankenfield Christopher James Officer (Chief Financial Officer) Option exercise +19,375 — —
Jan 1, 2026 Rene Russo Director, Officer (PRESIDENT AND CEO) Option exercise +44,250 — —
Jun 17, 2025 James Samuel Shannon Director Open-market purchase +25,000 $0.69 $17,250
Jun 16, 2025 James Samuel Shannon Director Open-market purchase +45,000 $0.69 $31,050
Jun 16, 2025 Rene Russo Director, Officer (PRESIDENT AND CEO) Open-market purchase +36,289 $0.68 $24,677
Jan 2, 2025 Frankenfield Christopher James Officer (Chief Financial Officer) Open-market sale −6,954 $0.98 $6,815
Jan 2, 2025 Brennan Kevin M. Officer (SVP, FINANCE AND ACCOUNTING) Open-market sale −1,803 $0.98 $1,767
Jan 1, 2025 Frankenfield Christopher James Officer (Chief Financial Officer) Option exercise +19,375 — —
Jan 1, 2025 Luptakova Katarina Officer (CHIEF MEDICAL OFFICER) Option exercise +16,625 — —
Jan 1, 2025 Rene Russo Director, Officer (PRESIDENT AND CEO) Option exercise +44,250 — —

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