Spero Therapeutics Inc.

Last updated September 27, 2026

Organization details

Legal name
Spero Therapeutics Inc.
Ownership
Public
Status
Active
Headquarters country
United States
Ticker symbol
SPRO
Primary stock exchange
Nasdaq

Identifiers

SEC CIK
0001701108

Board of directors

Chief executives

Ankit Mahadevia ยท CEO and President
Dates unknown
Sath Shukla ยท CEO and President
Dates unknown

Board connections

4 of this board's directors also sit on 8 other boards.

Network of Spero Therapeutics Inc.'s board connections Agios Pharmaceuticals Inc. Agios Pharmaceuticals... Akebia Therapeutics Inc. Akebia Therapeutics In... COMPASS Pathways Plc COMPASS Pathways Plc Crescent Biopharma Inc. Crescent Biopharma Inc... Larimar Therapeutics Inc. Larimar Therapeutics I... MacroGenics Inc. MacroGenics Inc. Protara Therapeutics Inc. Protara Therapeutics I... Tvardi Therapeutics Inc. Tvardi Therapeutics In... Cynthia Smith Cynthia Smith Frank E. Thomas Frank E. Thomas Kathleen Tregoning Kathleen Tregoning Scott Thomas Jackson Scott Thomas Jackson Spero Therapeutics Inc.
Shared director Other board Same sector

Insider trades

All notable trades →

From SEC Forms 4 and 5. Open-market purchases and sales are highlighted; grants, option exercises and shares withheld for tax are routine.

Bought, last 12 months
$0
0 purchases by 0 insiders
Sold, last 12 months
$552,042
9 sales by 2 insiders
Date Insider Transaction Shares Price Value
Aug 3, 2026 Zack Debra Officer (Chief Medical Officer) Grant or award +162,311 โ€” โ€”
Jun 23, 2026 Milind Deshpande Director Grant or award +10,000 โ€” โ€”
Jun 23, 2026 Kathleen Tregoning Director Grant or award +10,000 โ€” โ€”
Jun 23, 2026 Cynthia Smith Director Grant or award +10,000 โ€” โ€”
Jun 23, 2026 Patrick V.j.j. Vink Director Grant or award +10,000 โ€” โ€”
Jun 23, 2026 Frank E. Thomas Director Grant or award +10,000 โ€” โ€”
Jun 23, 2026 Scott Thomas Jackson Director Grant or award +10,000 โ€” โ€”
Jun 23, 2026 John C. Pottage Jr. Director Grant or award +10,000 โ€” โ€”
May 4, 2026 Rajavelu Esther Officer (See Remarks) Open-market sale โˆ’25,240 $2.51 $63,352
Feb 6, 2026 Rajavelu Esther Officer (See Remarks) Open-market sale โˆ’37,101 $2.36 $87,558
Feb 6, 2026 Keutzer Timothy Officer (Chief Operating Officer) Open-market sale โˆ’18,652 $2.36 $44,019
Feb 6, 2026 Rajavelu Esther Officer (See Remarks) Open-market sale โˆ’50,816 $2.36 $119,926
Feb 4, 2026 Keutzer Timothy Officer (Chief Operating Officer) Open-market sale โˆ’3,471 $2.24 $7,775
Feb 3, 2026 Keutzer Timothy Officer (Chief Operating Officer) Open-market sale โˆ’24,224 $2.14 $51,839
Feb 2, 2026 Keutzer Timothy Officer (Chief Operating Officer) Grant or award +68,000 โ€” โ€”

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