Spero Therapeutics Inc.

Last updated September 27, 2026

Organization details

Legal name
Spero Therapeutics Inc.
Ownership
Public
Status
Active
Sector (GICS)
Health Care
SIC code
2834 — Pharmaceutical Preparations
Jurisdiction of incorporation
Delaware
Headquarters city
Cambridge
Headquarters state / province
Massachusetts
Headquarters country
United States
Fiscal year end
December
Ticker symbol
SPRO
Primary stock exchange
Nasdaq

Identifiers

SEC CIK
0001701108

Board of directors

Chief executives

Ankit Mahadevia · CEO and President
Dates unknown
Sath Shukla · CEO and President
Dates unknown

Director election results

Annual meeting of June 23, 2026. Support is votes for as a share of votes for and against (or withheld). Below 80% is a clear protest.

Board connections

4 of this board's directors also sit on 8 other boards. 8 are in the same sector.

Network of Spero Therapeutics Inc.'s board connections Agios Pharmaceuticals Inc. Agios Pharmaceuticals... Akebia Therapeutics Inc. Akebia Therapeutics In... COMPASS Pathways Plc COMPASS Pathways Plc Crescent Biopharma Inc. Crescent Biopharma Inc... Larimar Therapeutics Inc. Larimar Therapeutics I... MacroGenics Inc. MacroGenics Inc. Protara Therapeutics Inc. Protara Therapeutics I... Tvardi Therapeutics Inc. Tvardi Therapeutics In... Cynthia Smith Cynthia Smith Frank E. Thomas Frank E. Thomas Kathleen Tregoning Kathleen Tregoning Scott Thomas Jackson Scott Thomas Jackson Spero Therapeutics Inc.
Shared director Other board Same sector

Insider trades

All notable trades →

From SEC Forms 4 and 5. Open-market purchases and sales are highlighted; grants, option exercises and shares withheld for tax are routine.

Bought, last 12 months
$0
0 purchases by 0 insiders
Sold, last 12 months
$499,087
9 sales by 2 insiders
Date Insider Transaction Shares Price Value
Nov 9, 2026 Esther Rajavelu Director, Officer (See Remarks) Open-market sale −40,851 $1.04 $42,485
Aug 3, 2026 Zack Debra Officer (Chief Medical Officer) Grant or award +162,311 — —
Jun 23, 2026 Milind Deshpande Director Grant or award +10,000 — —
Jun 23, 2026 Kathleen Tregoning Director Grant or award +10,000 — —
Jun 23, 2026 Cynthia Smith Director Grant or award +10,000 — —
Jun 23, 2026 Patrick V.j.j. Vink Director Grant or award +10,000 — —
Jun 23, 2026 Frank E. Thomas Director Grant or award +10,000 — —
Jun 23, 2026 Scott Thomas Jackson Director Grant or award +10,000 — —
Jun 23, 2026 John C. Pottage Jr. Director Grant or award +10,000 — —
May 4, 2026 Rajavelu Esther Officer (See Remarks) Open-market sale −25,240 $2.51 $63,352
Feb 6, 2026 Rajavelu Esther Officer (See Remarks) Open-market sale −37,101 $2.36 $87,558
Feb 6, 2026 Keutzer Timothy Officer (Chief Operating Officer) Open-market sale −18,652 $2.36 $44,019
Feb 6, 2026 Rajavelu Esther Officer (See Remarks) Open-market sale −50,816 $2.36 $119,926
Feb 4, 2026 Keutzer Timothy Officer (Chief Operating Officer) Open-market sale −3,471 $2.24 $7,775
Feb 3, 2026 Keutzer Timothy Officer (Chief Operating Officer) Open-market sale −24,224 $2.14 $51,839

Organizations in the same sector, closest in location and size first.

Questions about Spero Therapeutics Inc.

Who is the CEO of Spero Therapeutics Inc.?

Ankit Mahadevia is Spero Therapeutics Inc.'s CEO and President.

How many directors are on Spero Therapeutics Inc.'s board?

Spero Therapeutics Inc.'s board has 11 directors: Ankit Mahadevia, Cynthia Smith, Esther Rajavelu, Frank E. Thomas, John C. Pottage Jr., Kathleen Tregoning, Milind Deshpande, Patrick V.j.j. Vink, Sath Shukla, Scott Thomas Jackson and 1 other.

Are Spero Therapeutics Inc. insiders buying or selling shares?

Over the last 12 months, Spero Therapeutics Inc. insiders made no open-market purchases and sold $499,087 of shares in 9 sales on the open market, as reported to the SEC on Forms 4 and 5.

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