Oruka Therapeutics Inc.

Last updated September 27, 2026

Organization details

Legal name
Oruka Therapeutics Inc.
Former names
ARCA biopharma, Inc. Nuvelo Inc Hyseq Inc
Ownership
Public
Status
Active
Sector (GICS)
Health Care
SIC code
2834 — Pharmaceutical Preparations
Jurisdiction of incorporation
Delaware
Headquarters city
Menlo Park
Headquarters state / province
California
Headquarters country
United States
Fiscal year end
December
Ticker symbol
ORKA
Primary stock exchange
Nasdaq

Identifiers

SEC CIK
0000907654
EIN
36-3855489

Board of directors

Chief executives

Lawrence Otto Klein · President and CEO
Since August 2024

Director election results

Annual meeting of June 2, 2026. Support is votes for as a share of votes for and against (or withheld). Below 80% is a clear protest.

Board connections

9 of this board's directors also sit on 18 other boards. 18 are in the same sector.

Network of Oruka Therapeutics Inc.'s board connections Jade Biosciences Inc. Jade Biosciences Inc. Spyre Therapeutics Inc. Spyre Therapeutics Inc... Crescent Biopharma Inc. Crescent Biopharma Inc... Damora Therapeutics Inc. Damora Therapeutics In... Dianthus Therapeutics Inc. Dianthus Therapeutics... Korsana Biosciences Inc. Korsana Biosciences In... Viridian Therapeutics Inc. Viridian Therapeutics... Zenas BioPharma Inc. Zenas BioPharma Inc. Achieve Life Sciences Inc. Achieve Life Sciences... Black Diamond Therapeutics Inc. Black Diamond Therapeu... CRISPR Therapeutics AG CRISPR Therapeutics AG Cogent Biosciences Inc. Cogent Biosciences Inc... Corvus Pharmaceuticals Inc. Corvus Pharmaceuticals... Edgewise Therapeutics Inc. Edgewise Therapeutics... Enliven Therapeutics Inc. Enliven Therapeutics I... ICON plc ICON plc Cameron Turtle Cameron Turtle Christopher Nathan Martin Christopher Nathan M... Kristine M. Ball Kristine M. Ball Lawrence Otto Klein Lawrence Otto Klein Linda Grais Linda Grais Peter Evan Harwin Peter Evan Harwin Samarth Kulkarni Samarth Kulkarni Tomas Kiselak Tomas Kiselak Oruka Therapeutics Inc.
Shared director Other board Same sector +2 more in the list below

Insider trades

All notable trades →

From SEC Forms 4 and 5. Open-market purchases and sales are highlighted; grants, option exercises and shares withheld for tax are routine.

Bought, last 12 months
$0
0 purchases by 0 insiders
Sold, last 12 months
$339,541,582
122 sales by 7 insiders
Date Insider Transaction Shares Price Value
Nov 2, 2026 Lawrence Otto Klein Director, Officer (Chief Executive Officer) Option exercise +25,000 $7.80 $195,000
Nov 2, 2026 Lawrence Otto Klein Director, Officer (Chief Executive Officer) Open-market sale −6,466 $94.77 $612,794
Nov 2, 2026 Lawrence Otto Klein Director, Officer (Chief Executive Officer) Open-market sale −15,036 $95.64 $1,437,987
Nov 2, 2026 Lawrence Otto Klein Director, Officer (Chief Executive Officer) Open-market sale −2,442 $96.70 $236,147
Nov 2, 2026 Lawrence Otto Klein Director, Officer (Chief Executive Officer) Open-market sale −756 $97.45 $73,676
Nov 2, 2026 Lawrence Otto Klein Director, Officer (Chief Executive Officer) Open-market sale −300 $98.40 $29,521
Oct 20, 2026 Quinlan Paul T Officer (General Counsel) Option exercise +9,000 $7.80 $70,200
Oct 20, 2026 Quinlan Paul T Officer (General Counsel) Open-market sale −400 $74.90 $29,960
Oct 20, 2026 Quinlan Paul T Officer (General Counsel) Open-market sale −500 $76.12 $38,059
Oct 20, 2026 Quinlan Paul T Officer (General Counsel) Open-market sale −1,000 $77.21 $77,205
Oct 20, 2026 Quinlan Paul T Officer (General Counsel) Open-market sale −4,100 $78.79 $323,037
Oct 20, 2026 Quinlan Paul T Officer (General Counsel) Open-market sale −3,000 $79.49 $238,474
Oct 12, 2026 Agarwal Arjun Officer (Senior Vice President, Finance) Option exercise +8,541 $12.50 $106,763
Oct 12, 2026 Agarwal Arjun Officer (Senior Vice President, Finance) Option exercise +1,458 $34.39 $50,141
Oct 12, 2026 Agarwal Arjun Officer (Senior Vice President, Finance) Open-market sale −5,741 $80.03 $459,453

Organizations in the same sector, closest in location and size first.

Questions about Oruka Therapeutics Inc.

Who is the CEO of Oruka Therapeutics Inc.?

Lawrence Otto Klein has been Oruka Therapeutics Inc.'s President and CEO since August 2024.

How many directors are on Oruka Therapeutics Inc.'s board?

Oruka Therapeutics Inc.'s board has 15 directors: Anders D. Hove, Cameron Turtle, Carl Dambkowski, Christopher Nathan Martin, Daniel J. Mitchell, Jacob Ma-Weaver, James P. Flynn, Kristine M. Ball, Lawrence Otto Klein, Linda Grais and 5 others.

Are Oruka Therapeutics Inc. insiders buying or selling shares?

Over the last 12 months, Oruka Therapeutics Inc. insiders made no open-market purchases and sold $339.5 million of shares in 122 sales on the open market, as reported to the SEC on Forms 4 and 5.

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